Z. officinale has been widely used in Ayurvedic, Chinese and Tibb-Yunani system of medicines

t

WHAT

Botanical name : Zingiber officinale Rosc.
Family : Zingiberaceae
Common Name : Ginger
Part used : Rhizome

Zinberin® is standardized Z. officinale extract. Z. officinale has been widely used  in Ayurvedic, Chinese and Tibb-Yunani system of medicines for the treatment of wide array ailments.

Phyto constituents

Ginger contains non-volatile bioactive constituents including the gingerols, shogaol, paradols and zingerone that produce a ‘‘hot’’ sensation in the mouth.[1,2] The volatile oil components of Z. officinale contain sesquiterpene hydrocarbons, predominantly zingeberene, curcumene and farnesene. Aromatic constituent like zingiberol, gingediol, monoacyldigalactosyl- glycerol, diarylheptanoids and phytosterols have also been identified.

Clinical indication

Rhizome of Z. officinale has been reported to have antioxidant, anti-inflammatory, anti-cancer, immunomodulatory, antiapoptotic and antitumorigenic properties.  It is also used for the treatment of headaches, nausea, febrile conditions like colds, arthritis, rheumatic disorders and muscular discomfort.[4] Gingerol has been found to possess a variety of interesting pharmacological effects, for example, antipyretic, cardiotonic effects, and inhibition of spontaneous motor activity and prostaglandin biosynthesis.

Recommended dose

For motion sickness fresh or dried rhizome of 2–4 g daily or 500 mg powdered dry extract, 30 minutes before travel, and then 500 mg every 4 hours until end of travel should be consumed.

References

Langner et al. 1998. Ginger: history and use. Advances in Therapy 15: 25– 44.

Govindarajan V. 1982. Ginger-chemistry technology and quality evaluation: Part-I CRC. Food Sci and Nutri. 17: 1–96.

Govindarajan, V., 1982. Ginger-chemistry technology and quality evaluation: Part-I CRC. Food Science and Nutrition. 17, 1–96.

Pandit et al. 2012. Cytochrome P450 inhibitory potential of selected Indian spices – possible food drug interaction. Food res Int. 45(1):69-74

Kiuchi et al. 1992. Inhibition of prostaglandin and leukotriene biosynthesis by gingerols and diarylheptanoids. Chemical and Pharma Bull. 40:387–391.

European Medicines Agency, 2012. Assessment report on Zingiber officinale Roscoe, rhizome EMA/HMPC/577856/2010. 1-50

American Botanical Council (ABC). 2003. The ABC Clinical Guide to Herbs. 171-183