Kacip Fatimah Extract

Kacip Fatimah Extract INQUIRE

General description:

Botanical Name : Labisia pumila Family : Myrsinaceae Common Name : Kacip Fatimah Part used : Leaf and stem L. pumila can be widely found throughout the rain forest of Indochina, particularly Malaysia. It grows wildly at 80-100 meter above the sea level. Traditionally this plant is being used by women to promote health of female reproductive system, men of several ethnic groups are also consumed to increase stamina

Phytoconstituents:

Phytochemicals such as phenolic, flavonoid, carotenoids, ascorbic acids, saponin, alkenyl compounds and benzoquinone derivatives of Kacip Fatimah contribute numerous pharmacological activities. Essential oil is rich in sesquiterpenes alcohols such as Longiborneol, geranyl linalool and T-Cadinol. Other constituents like diterpenes alcohol, Isoabienol, β-Santalol acetate and 1,4-trans-6-methoxyliso-calamene have been reported from kacip Fatima.

Pharmacological activities:

L. pumila has been widely used by the traditional practitioners as a remedy for involution of birth channel, delay fertility and to regain body strength. It is being used to reduce excessive gas in the body, treat flatulence, dysentery, dysmenorrheal and gonorrhea. The extract from the plant is used as an energy drink.[2] A randomized, double-blind, placebo-controlled study was conducted with 280 mg/day L. pumila during 6 months in postmenopausal Malay women. The blood pressure, body mass index, waist circumference, fasting blood sugar, lipid profile, and hormonal profile (follicle stimulating hormone/luteinizing hormone/estradiol) were measured during the visits. Study concluded that intake of L. pumila was found to provide benefit in reducing the triglyceride (TG) values.[3] Another randomized, double-blind, placebo-controlled, parallel group, 16-week study in healthy pre- and postmenopausal women aged 40-60 years was conducted in Kelantan, Malaysia to determine the efficacy and safety of L. pumila extract for improving quality of life, cardiovascular and hormonal balance. The subjects were randomized to 400 mg propriety extract of L. pumila or placebo. Improvements were seen in the cardiovascular parameters, and the safety profiles were normal. Postmenopausal women supplemented with L. pumila showed no changes in gynecological relevant hormones luteinizing hormone (LH), follicle-stimulating hormone (FSH), and 17β-Estradiol. Water extract of L.pumila was shown to be safe and effective for improving several parameters of quality of life and cardiovascular risks factors.

References :

  1. Abdullah et al., 2013. Labisia pumila: A Review on its Traditional, Phytochemical and Biological Uses. World Appl. Sci. J., 27 (10): 1297-1306, 2013
  2. Pattiram et al., 2011. Identification of the aroma-active constituents of the essential oils of Water Dropwort (Oenanthe javanica) and ‘Kacip Fatimah’ (Labisia pumila). International Food Research Journal 18(3): 1021-1026 (2011)
  3. Abdul Kadir et al., 2012. The Effect of Labisia pumila var. alata on Postmenopausal Women: A Pilot Study. Evid Based Complement Alternat Med. 2012;2012:216525. doi: 10.1155/2012/216525.
  4. Norhayati et al., 2014. Efficacy and safety of Labisia pumila var alata water extract among pre- and postmenopausal women. J Med Food. 17(8):929-38.

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